Description

(2-tert-Butoxycarbonylamino-Pyridin-4-Yl)-Acetic Acid CAS NO 887580-70-3 is a high-purity, protected amino acid derivative featuring a pyridine core and a Boc-protected amine group. This compound serves as a critical pharmaceutical intermediate and custom synthesis building block for medicinal chemistry research and development. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries for constructing complex molecules, particularly in peptide mimetics and small molecule drug discovery programs.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs) and novel drug candidates.
• Peptidomimetic Synthesis: Used to incorporate modified amino acid structures into peptide chains to enhance stability, bioavailability, or biological activity.
• Custom Chemical Synthesis: Serves as a versatile starting material or reagent for contract research organizations (CROs) and fine chemical manufacturers.
• Medicinal Chemistry Research: Enables the exploration of structure-activity relationships (SAR) in drug discovery projects targeting various disease pathways.
• Bioconjugation & Probe Development: Can be utilized for labeling or modifying biomolecules in biochemical research and diagnostic applications.
• Academic Research: Employed in university and institutional labs for synthetic organic chemistry studies and methodology development.

Basic Information

Product Name	(2-tert-Butoxycarbonylamino-Pyridin-4-Yl)-Acetic Acid
CAS No.	887580-70-3
Molecular Formula	C12H16N2O4
Molecular Weight	252.27 g/mol
Synonyms	2-[(tert-Butoxycarbonyl)amino]-4-pyridinylacetic Acid; 2-(Boc-amino)-4-pyridylacetic Acid; 2-((tert-Butoxycarbonyl)amino)isonicotinic Acid Derivative; (2-Boc-amino-4-pyridyl)acetic Acid; 4-Pyridylacetic Acid, 2-[(tert-butoxycarbonyl)amino]-; Boc-4-Pyridylglycine Derivative; 2-(N-Boc-amino)pyridin-4-ylacetic Acid; N-Boc-2-aminoisonicotinic Acid Ethyl Ester Hydrolysis Product
EINECS	Contact for details

Quality Control

Our (2-tert-Butoxycarbonylamino-Pyridin-4-Yl)-Acetic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and consistent identity. Certificates of Analysis (COA) detailing all specifications are provided and available upon request. We support compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive). For long-term storage, consider storing under an inert atmosphere to maintain optimal purity and stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.