Description

[[(6-Bromo)-2-Pyridinyl]Methyl]-Carbamic Acid, 1,1-Dimethylethyl Ester is a high-purity, advanced pharmaceutical intermediate and versatile organic building block. Its core value lies in its functionalized pyridine and carbamate structure, which is critical for constructing complex molecules in medicinal chemistry. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for the synthesis of active pharmaceutical ingredients (APIs) and novel bioactive compounds.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of complex drug candidates, particularly those targeting neurological and oncological pathways.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and for introducing the bromo-pyridinyl moiety into lead compounds for further functionalization.
• Agrochemical Synthesis: Serves as a precursor in the development of novel pesticides and herbicides, leveraging its heterocyclic structure.
• Ligand and Catalyst Development: Utilized in the preparation of specialized ligands for metal-catalyzed cross-coupling reactions, such as Suzuki or Buchwald-Hartwig amination.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis projects requiring a protected amine functionality on a brominated pyridine scaffold.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme function and biological pathways.

Basic Information

Product Name	[[(6-Bromo)-2-Pyridinyl]Methyl]-Carbamic Acid, 1,1-Dimethylethyl Ester
CAS No.	887580-31-6
Molecular Formula	C12H17BrN2O2
Molecular Weight	301.18 g/mol
Synonyms	tert-Butyl N-[[6-bromo-2-pyridyl]methyl]carbamate; N-[(6-Bromo-2-pyridinyl)methyl]carbamic Acid 1,1-Dimethylethyl Ester; Boc-6-Bromo-2-picolylamine; Boc-AMine-PEG2-azide; (6-Bromo-pyridin-2-ylmethyl)-carbamic acid tert-butyl ester; 2-Pyridinemethanamine, 6-bromo-, N-BOC derivative; BOC-6-Bromo-2-Picolylamine; tert-Butyl (6-bromopicolyl)carbamate
EINECS	Contact for details

Quality Control

Our [[(6-Bromo)-2-Pyridinyl]Methyl]-Carbamic Acid, 1,1-Dimethylethyl Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports applications requiring GMP-grade starting materials and compliance with ICH guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.