Description

tert-Butyl 5-(Aminomethyl)Nicotinate is a high-purity chemical intermediate featuring a nicotinate core with both tert-butyl ester and aminomethyl functional groups. This compound is valued for its versatility as a key building block in the synthesis of complex molecules, particularly in pharmaceutical research and development. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting neurological and metabolic disorders.
• Agrochemical Synthesis: Used in the research and development of novel pesticides and herbicides, leveraging its functionalized pyridine structure.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Peptidomimetic Research: The aminomethyl group allows for incorporation into peptide backbones to create modified peptides with enhanced stability or activity.
• Chemical Biology Probes: Utilized in the development of molecular probes and tags for studying biological processes and target engagement.
• Fine Chemical Production: Acts as a versatile intermediate for the custom synthesis of specialty chemicals and advanced materials.

Basic Information

Product Name	tert-Butyl 5-(Aminomethyl)Nicotinate
CAS No.	887579-76-2
Molecular Formula	C11H16N2O2
Molecular Weight	208.26 g/mol
Synonyms	5-(Aminomethyl)nicotinic acid tert-butyl ester; tert-Butyl 5-(aminomethyl)pyridine-3-carboxylate; 3-Pyridinecarboxylic acid, 5-(aminomethyl)-, 1,1-dimethylethyl ester; 1,1-Dimethylethyl 5-(aminomethyl)-3-pyridinecarboxylate; 5-(Aminomethyl)nicotinic acid 1,1-dimethylethyl ester; Nicotinic acid, 5-(aminomethyl)-, tert-butyl ester
EINECS	Contact for details

Quality Control

Our tert-Butyl 5-(Aminomethyl)Nicotinate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis by GC. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, ensuring compliance with the stringent requirements of research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.