Description

tert-Butyl-5-Cyanonicotinate is a high-purity chemical intermediate featuring a nicotinate core functionalized with a cyano group and a tert-butyl ester. This compound matters for its role as a versatile building block in advanced organic synthesis, enabling the construction of complex molecular architectures. It is primarily needed by research and development chemists and process engineers in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, leveraging its pyridine-based structure.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in catalytic processes and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the development of organic electronic materials and functional polymers.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	tert-Butyl-5-Cyanonicotinate
CAS No.	887579-69-3
Molecular Formula	C11H12N2O2
Molecular Weight	204.23 g/mol
Synonyms	5-Cyano-nicotinic acid tert-butyl ester; tert-Butyl 5-cyanopyridine-3-carboxylate; 3-Pyridinecarboxylic acid, 5-cyano-, 1,1-dimethylethyl ester; 5-Cyanopyridine-3-carboxylic acid tert-butyl ester; Nicotinic acid, 5-cyano-, tert-butyl ester
EINECS	Contact for details

Quality Control

Our tert-Butyl-5-Cyanonicotinate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay and impurity profiles. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.