Description

3,4-Dihydro-1H-Pyrido[4,3-B]Azepine-2,5-Dione is a high-purity, heterocyclic organic compound serving as a critical advanced pharmaceutical intermediate. This compound matters for its role as a sophisticated building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex molecular architectures. Pharmaceutical R&D laboratories and fine chemical manufacturers need it to develop next-generation drug candidates with potential applications in central nervous system (CNS) and oncological research.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of novel drug candidates, especially in medicinal chemistry programs.
• API Synthesis: Serves as a core structural scaffold in the multi-step synthesis of complex Active Pharmaceutical Ingredients (APIs).
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new therapeutic agents.
• Preclinical Development: Essential for producing batches of candidate compounds for pharmacological and toxicological evaluation.
• Chemical Biology Probes: Can be utilized to develop molecular probes for studying biological pathways and target validation.
• Contract Research & Manufacturing (CRAM): Supplied to CDMOs and CROs engaged in custom synthesis and process development for clients.

Basic Information

Item	Detail
Product Name	3,4-Dihydro-1H-Pyrido[4,3-B]Azepine-2,5-Dione
CAS No.	887576-83-2
Molecular Formula	C9H8N2O2
Molecular Weight	176.17 g/mol
Synonyms	1H-Pyrido[4,3-b]azepine-2,5-dione, 3,4-dihydro-; 3,4-Dihydro-1H-pyrido[4,3-b]azepine-2,5-dione; 2,5-Dioxo-3,4-dihydro-1H-pyrido[4,3-b]azepine; Pyridoazepinedione derivative; Azepino[4,5-b]pyridine-2,5-dione, 1,3,4,6-tetrahydro- (related); Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our 3,4-Dihydro-1H-Pyrido[4,3-B]Azepine-2,5-Dione is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the exacting standards required for pharmaceutical R&D. Certificates of Analysis (COA) documenting batch-specific results are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.