Description

2,6-Dibromo-3-Picoline is a halogenated pyridine derivative that serves as a versatile and critical building block in advanced organic synthesis. Its value lies in the strategic positioning of bromine atoms on the pyridine ring, enabling selective functionalization for the construction of complex molecular architectures. This intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of active ingredients, ligands, and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Building block for creating novel herbicides, fungicides, and insecticides that require halogenated heterocyclic cores.
• Ligand and Catalyst Development: Used to prepare specialized pyridine-based ligands for transition metal catalysis in fine chemical production.
• Material Science Research: Intermediate in the development of organic electronic materials, such as those used in OLEDs or conductive polymers.
• Cross-Coupling Reactions: Serves as a substrate in Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form biaryl systems.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological systems and enzyme function.

Basic Information

Product Name	2,6-Dibromo-3-Picoline
CAS No.	887571-15-5
Molecular Formula	C6H5Br2N
Molecular Weight	250.92 g/mol
Synonyms	2,6-Dibromo-3-methylpyridine; 3-Methyl-2,6-dibromopyridine; 2,6-Dibromo-3-picoline; 3-Picoline, 2,6-dibromo-; 2,6-Dibromo-3-methylpyridine; Pyridine, 2,6-dibromo-3-methyl-
EINECS	Contact for details

Quality Control

Our 2,6-Dibromo-3-Picoline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications. We support cGMP standards for pharmaceutical applications and can accommodate custom purity requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in opaque packaging or amber glass.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.