Description

5-Fluoro-1H-Pyrrolo[3,2-B] Pyridine is a high-value, fluorinated heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in its unique fused pyrrolopyridine scaffold, which serves as a privileged structure for modulating the biological activity and physicochemical properties of target molecules. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the discovery and development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for constructing novel drug candidates, particularly in oncology, CNS disorders, and antiviral research.
• Agrochemical Research: Used in the synthesis of advanced herbicides, fungicides, and insecticides, leveraging the fluorine atom for enhanced bioactivity and environmental stability.
• Material Science Precursor: Serves as a building block for creating specialized organic electronic materials, such as ligands for OLEDs or conductive polymers.
• Chemical Biology Probe: Utilized in medicinal chemistry to create tool compounds for studying enzyme mechanisms and protein-ligand interactions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds and complex molecules on a commercial scale.

Basic Information

Product Name	5-Fluoro-1H-Pyrrolo[3,2-B] Pyridine
CAS No.	887570-96-9
Molecular Formula	C7H5FN2
Molecular Weight	136.13 g/mol
Synonyms	5-Fluoropyrrolo[3,2-b]pyridine; 5-Fluoro-1H-pyrrolo[3,2-b]pyridine; 5-Fluoro-7-azaindole; 5-Fluoro-1H-pyrrolo[3,2-b]pyridin; 5-Fluoro-7-azaindole; 1H-Pyrrolo[3,2-b]pyridine, 5-fluoro-; 887570-96-9
EINECS	Contact for details

Quality Control

Our 5-Fluoro-1H-Pyrrolo[3,2-B] Pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our commitment to supply chain reliability and documentation transparency supports your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound may be light-sensitive and hygroscopic; prolonged exposure to light, moisture, or extreme temperatures should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder/crystals
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Individual impurity ≤ 1.0%
Total Impurities	≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.