Description

[1-(1H-Imidazol-2-Yl)-Ethyl]-Carbamic Acid tert-Butyl Ester is a sophisticated heterocyclic building block featuring a protected carbamate group and an imidazole moiety. This compound is of significant value in medicinal chemistry and pharmaceutical research as a key intermediate for the synthesis of novel drug candidates, particularly those targeting enzymatic pathways. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of protease inhibitors, kinase inhibitors, and other bioactive molecules.
• Medicinal Chemistry Research: Used in high-throughput screening and combinatorial chemistry for lead optimization and structure-activity relationship (SAR) studies.
• Peptidomimetic Synthesis: Serves as a protected amino acid analog for constructing peptide-like compounds with enhanced metabolic stability.
• Agrochemical Development: Employed in the research and development of new fungicides and herbicides.
• Chemical Biology Probes: Utilized to create labeled compounds for studying enzyme mechanisms and cellular processes.
• Custom Synthesis & Contract Manufacturing: A starting material for the GMP or non-GMP production of advanced intermediates for clinical trial materials.

Basic Information

Product Name	[1-(1H-Imidazol-2-Yl)-Ethyl]-Carbamic Acid tert-Butyl Ester
CAS No.	887344-33-4
Molecular Formula	C10H17N3O2
Molecular Weight	211.26 g/mol
Synonyms	tert-Butyl N-[1-(1H-imidazol-2-yl)ethyl]carbamate; 1-(1H-Imidazol-2-yl)ethyl-carbamic acid tert-butyl ester; Boc-Imidazole-Ala-OH tert-butyl ester; N-Boc-1-(1H-imidazol-2-yl)ethylamine; 2-(1-((tert-Butoxycarbonyl)amino)ethyl)-1H-imidazole; (1-(1H-Imidazol-2-yl)ethyl)carbamic Acid 1,1-Dimethylethyl Ester
EINECS	Contact for details

Quality Control

Our [1-(1H-Imidazol-2-Yl)-Ethyl]-Carbamic Acid tert-Butyl Ester is produced under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency suitable for research and development. Certificates of Analysis (COA) with detailed specifications are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.