Description

3-Pyridin-3-Yl Morpholine is a versatile heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of novel pharmacologically active molecules, particularly in medicinal chemistry. Pharmaceutical researchers and fine chemical manufacturers need it for constructing complex molecular architectures, such as kinase inhibitors and other targeted therapeutics. Its unique fused pyridine-morpholine structure offers valuable synthetic handles for creating diverse chemical libraries.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for kinase inhibitors and central nervous system (CNS) targeted drugs.
• Medicinal Chemistry Research: Used as a core scaffold or building block for constructing novel chemical entities in drug discovery and lead optimization programs.
• Agrochemical Development: Serves as an intermediate in the research and synthesis of new generation herbicides and fungicides.
• Ligand Synthesis for Catalysis: Employed in the preparation of specialized ligands for transition metal catalysis, enabling novel synthetic transformations.
• Material Science Research: Investigated as a monomer or functional component in the development of advanced polymers and functional organic materials.

Basic Information

Product Name	3-Pyridin-3-Yl Morpholine
CAS No.	887344-25-4
Molecular Formula	C9H12N2O
Molecular Weight	164.20 g/mol
Synonyms	3-(Morpholin-4-yl)pyridine; 3-(4-Morpholinyl)pyridine; 4-(Pyridin-3-yl)morpholine; Morpholine, 4-(3-pyridinyl)-; Pyridin-3-yl-morpholine; 3-Morpholin-4-yl-pyridine; 3-Pyridylmorpholine
EINECS	Contact for details

Quality Control

Our 3-Pyridin-3-Yl Morpholine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to confirm identity and purity. Certificates of Analysis (COA) detailing all test results are provided with every shipment. We adhere to cGMP principles for pharmaceutical intermediates, ensuring our product meets the stringent requirements of advanced research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.