Description

1-[(tert-Butyl)Oxycarbonyl]-3-Pyridin-2-Ylmethylpiperidine-3-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate featuring a piperidine core with both Boc (tert-butoxycarbonyl) and carboxylic acid protecting groups. This compound is critical for medicinal chemistry research and development, serving as a versatile building block for the synthesis of complex bioactive molecules. It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers for creating novel drug candidates, particularly in the areas of central nervous system (CNS) and antiviral therapies.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs) and novel drug candidates.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new therapeutic agents.
• Protease Inhibitor Synthesis: Serves as a precursor in the development of protease inhibitors due to its specific stereochemistry and functional groups.
• Ligand and Receptor Modulator Development: Employed in the creation of ligands targeting G-protein coupled receptors (GPCRs) and other biological targets.
• Peptidomimetic Chemistry: Integral for designing and synthesizing peptidomimetics, which are molecules that mimic the structure and function of peptides.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.

Basic Information

Item	Details
Product Name	1-[(tert-Butyl)Oxycarbonyl]-3-Pyridin-2-Ylmethylpiperidine-3-Carboxylic Acid
CAS No.	887344-17-4
Molecular Formula	C18H26N2O4
Molecular Weight	334.41 g/mol
Synonyms	1-Boc-3-(Pyridin-2-ylmethyl)piperidine-3-carboxylic Acid; 1-N-Boc-3-(2-Pyridylmethyl)-3-piperidinecarboxylic Acid; 3-[(Pyridin-2-yl)methyl]-1-[(2-methylpropan-2-yl)oxycarbonyl]piperidine-3-carboxylic Acid; tert-Butyl 3-(carboxy)-3-(2-pyridylmethyl)piperidine-1-carboxylate; 1-Boc-3-(2-Picolyl)piperidine-3-carboxylic Acid; 1-(tert-Butoxycarbonyl)-3-(pyridin-2-ylmethyl)piperidine-3-carboxylic Acid
EINECS	Contact for details

Quality Control

Our 1-[(tert-Butyl)Oxycarbonyl]-3-Pyridin-2-Ylmethylpiperidine-3-Carboxylic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for pharmaceutical R&D. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.