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3-Bromo-4-(3'-Fluorophenyl)Pyridine CAS NO 887267-21-2


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CAS No.:887267-21-2

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

3-Bromo-4-(3'-Fluorophenyl)Pyridine is a high-value halogenated pyridine derivative, serving as a critical building block in modern synthetic chemistry. Its molecular architecture, featuring both bromine and fluorine substituents on an aromatic pyridine core, makes it an indispensable intermediate for constructing complex molecules. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs), agrochemicals, and advanced materials.

Application

  • Pharmaceutical Intermediate: A key synthon in the synthesis of novel drug candidates, particularly in kinase inhibitor and central nervous system (CNS) active compound research.
  • Agrochemical Research: Used in the development of next-generation herbicides, fungicides, and insecticides, leveraging its halogenated structure for bioactivity.
  • Material Science: Serves as a precursor for organic electronic materials, including ligands for OLEDs and charge-transport materials.
  • Chemical Synthesis: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) to introduce the 3-bromo-4-arylpyridine moiety into larger molecular frameworks.
  • Ligand & Catalyst Development: Utilized in the preparation of specialized ligands for transition metal catalysis.
  • Life Science Research: Acts as a biochemical tool compound for probing biological pathways and protein interactions.

Basic Information

Product Name 3-Bromo-4-(3'-Fluorophenyl)Pyridine
CAS No. 887267-21-2
Molecular Formula C11H7BrFN
Molecular Weight 252.08 g/mol
Synonyms 4-(3-Fluorophenyl)-3-bromopyridine; 3-Bromo-4-(3-fluorophenyl)pyridine; 3-Bromo-4-(3-fluorophenyl)pyridine; Pyridine, 3-bromo-4-(3-fluorophenyl)-; 887267-21-2; 3-Br-4-(3-F-Ph)Py
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Quality Control

Every batch of 3-Bromo-4-(3'-Fluorophenyl)Pyridine is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the compound meets the high-purity standards required for research and development. A detailed Certificate of Analysis (COA) is supplied with each shipment, confirming identity, purity, and impurity profile. Our quality protocols are designed to support cGMP and ISO guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat and incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Purity (HPLC) ≥ 97.0%
Related Substances (HPLC) Total impurities ≤ 3.0%
Water Content (KF) ≤ 0.5%
Residue on Ignition ≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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