Description

3-Bromo-4-(4'-Fluorophenyl)Pyridine is a high-value halogenated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its molecular architecture, featuring both bromine and fluorine substituents, makes it an indispensable intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly in kinase inhibitor and central nervous system (CNS) therapeutic research.
• Agrochemical Development: Used to create novel herbicides, fungicides, and insecticides by introducing the fluorophenyl-pyridine scaffold.
• Material Science: Serves as a monomer or functionalizing agent in the production of specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Research: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and as a versatile scaffold for medicinal chemistry and structure-activity relationship (SAR) studies.
• Ligand Synthesis: Useful for preparing sophisticated ligands used in catalysis and coordination chemistry.

Basic Information

Product Name	3-Bromo-4-(4'-Fluorophenyl)Pyridine
CAS No.	887267-20-1
Molecular Formula	C11H7BrFN
Molecular Weight	252.08 g/mol
Synonyms	4-(4-Fluorophenyl)-3-bromopyridine; 3-Bromo-4-(4-fluorophenyl)pyridine; 4-(4-Fluorophenyl)-3-bromo-pyridine; Pyridine, 3-bromo-4-(4-fluorophenyl)-; 887267-20-1; 3-Bromo-4-(p-fluorophenyl)pyridine
EINECS	Contact for details

Quality Control

Our production of 3-Bromo-4-(4'-Fluorophenyl)Pyridine adheres to stringent quality management protocols. Each batch is subjected to comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with every shipment, documenting all critical quality attributes. Our facilities operate under cGMP principles where applicable, ensuring traceability and reliability for our global B2B partners.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.