Description

3-Phenyl-1,4,8-Triazaspiro[4.5]Dec-3-En-2-One is a high-value, nitrogen-containing heterocyclic compound featuring a unique spirocyclic architecture. This structural complexity makes it a critical intermediate for advanced research and development in pharmaceutical chemistry. It is primarily sought after by R&D chemists and process development scientists working in medicinal chemistry and agrochemical discovery. The compound serves as a versatile building block for synthesizing novel molecules with potential biological activity.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of new active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and oncology targets.
• Medicinal Chemistry Scaffold: Used as a core structural motif for constructing compound libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• Agrochemical Research: Serves as a building block in the synthesis of novel herbicides, fungicides, and insecticides, leveraging its complex heterocyclic structure.
• Chemical Biology Probe: Utilized in the development of molecular probes to study enzyme function and biological pathways.
• Academic & Institutional Research: Employed in universities and research institutes for fundamental studies in organic synthesis and heterocyclic chemistry.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring specialized spirocyclic intermediates.

Basic Information

Product Name	3-Phenyl-1,4,8-Triazaspiro[4.5]Dec-3-En-2-One
CAS No.	887220-96-4
Molecular Formula	C15H17N3O
Molecular Weight	255.32 g/mol
Synonyms	3-Phenyl-1,4,8-triazaspiro[4.5]dec-3-en-2-one; 1,4,8-Triazaspiro[4.5]dec-3-en-2-one, 3-phenyl-; Spiro[4.5]dec-3-ene-2-one, 3-phenyl-1,4,8-triaza-; 3-Phenyl-1,4,8-triazaspiro[4.5]dec-3-en-2-one; 887220-96-4; 3-Phenyl-1,4,8-triazaspiro[4.5]decan-2-one (tautomer reference)
EINECS	Contact for details

Quality Control

Our 3-Phenyl-1,4,8-Triazaspiro[4.5]Dec-3-En-2-One is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. For projects requiring specific regulatory support, we can discuss compliance with relevant guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.