Description

5-(6-Hydroxy-5-Methyl-Pyridin-3-Yl)-Thiophene-2-Carboxylic Acid is a high-purity heterocyclic building block of significant interest in advanced organic synthesis. Its molecular architecture, featuring both pyridine and thiophene moieties, makes it a critical intermediate for constructing complex pharmacologically active molecules. This compound is primarily sought by pharmaceutical R&D and fine chemical manufacturers engaged in developing new therapeutic agents and high-value specialty chemicals.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and anti-inflammatory targets.
• Agrochemical Research: Used in the development of new generation herbicides and fungicides, leveraging its heterocyclic structure for bioactivity.
• Material Science: Serves as a precursor for functionalized monomers in the production of conductive polymers and advanced organic electronic materials.
• Ligand Synthesis: Utilized in creating complex chelating ligands for catalysis and metal-organic frameworks (MOFs).
• Bioconjugation Chemistry: The carboxylic acid group enables its use as a linker molecule for attaching functional groups to biomolecules in diagnostic reagent development.

Basic Information

Product Name	5-(6-Hydroxy-5-Methyl-Pyridin-3-Yl)-Thiophene-2-Carboxylic Acid
CAS No.	887201-37-8
Molecular Formula	C12H9NO3S
Molecular Weight	247.27 g/mol
Synonyms	5-(6-Hydroxy-5-methylpyridin-3-yl)thiophene-2-carboxylic acid; 2-Thiophenecarboxylic acid, 5-(6-hydroxy-5-methyl-3-pyridinyl)-; 5-(6-Hydroxy-5-methyl-3-pyridyl)thiophene-2-carboxylic acid; 5-(5-Methyl-6-oxo-1,6-dihydropyridin-3-yl)thiophene-2-carboxylic acid (tautomer); 3-(5-Carboxythiophen-2-yl)-5-methylpyridin-2-ol; CAS 887201-37-8
EINECS	Contact for details

Quality Control

Our production of 5-(6-Hydroxy-5-Methyl-Pyridin-3-Yl)-Thiophene-2-Carboxylic Acid adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC for purity and NMR/IR for structural confirmation, to ensure consistent high quality and reliable performance in your synthesis. A detailed Certificate of Analysis (COA) is provided with each shipment to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The compound may be light-sensitive and hygroscopic; therefore, containers should be kept sealed under an inert atmosphere for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.