Description

tert-Butyl 2,4-Dioxo-1,3,7-Triazaspiro[4.5]Decane-7-Carboxylate is a high-value, advanced pharmaceutical intermediate characterized by its complex spirocyclic and heterocyclic architecture. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated molecular scaffolds. It is primarily sought by research institutions and pharmaceutical manufacturers engaged in the development of new drug candidates, especially within oncology and central nervous system (CNS) research.

Application

• Key Intermediate in API Synthesis: Serves as a crucial building block for constructing complex drug molecules, particularly protease inhibitors and kinase inhibitors.
• Pharmaceutical Research & Development: Used in medicinal chemistry for lead optimization and the creation of novel chemical entities with potential therapeutic activity.
• Pre-clinical Drug Development: Employed in the synthesis of compounds for pharmacological profiling, toxicology studies, and formulation development.
• Contract Manufacturing (CMO): Supplied to contract research and manufacturing organizations (CROs/CMOs) for custom synthesis projects.
• Academic Research: Utilized in university and institutional labs for studying heterocyclic chemistry and developing new synthetic methodologies.

Basic Information

Item	Detail
Product Name	tert-Butyl 2,4-Dioxo-1,3,7-Triazaspiro[4.5]Decane-7-Carboxylate
CAS No.	887120-96-9
Molecular Formula	C12H19N3O4
Molecular Weight	269.30 g/mol
Synonyms	7-Boc-2,4-dioxo-1,3,7-triazaspiro[4.5]decane; 1,3,7-Triazaspiro[4.5]decane-2,4-dione, 7-(1,1-dimethylethyl) ester; tert-Butyl 2,4-dioxo-1,3,7-triazaspiro[4.5]decane-7-carboxylate; 7-(tert-Butoxycarbonyl)-1,3,7-triazaspiro[4.5]decane-2,4-dione; Boc-protected triazaspirodecanedione; CAS 887120-96-9
EINECS	Contact for details

Quality Control

Every batch of tert-Butyl 2,4-Dioxo-1,3,7-Triazaspiro[4.5]Decane-7-Carboxylate is manufactured under strict quality management systems. We provide comprehensive analytical documentation to ensure traceability and reliability for your critical R&D and cGMP manufacturing processes. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for each lot, supporting regulatory submissions and quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.