Description

2,7-Diazaspiro[4.5]Decan-1-One is a high-value, nitrogen-containing spirocyclic compound that serves as a critical building block in advanced organic synthesis. Its unique bridged bicyclic structure makes it a versatile intermediate for constructing complex molecular architectures with specific three-dimensional properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) and other therapeutic areas requiring complex heterocyclic scaffolds.
• Medicinal Chemistry Building Block: Used to introduce a rigid, three-dimensional spirocyclic framework into molecules, which can improve target binding affinity, metabolic stability, and other pharmacokinetic properties.
• Agrochemical Research: Employed in the synthesis of novel herbicides, fungicides, or insecticides where the diazaspiro structure may confer unique biological activity.
• Chemical Biology Probe Development: Utilized as a core structure for creating molecular probes to study enzyme function or protein-protein interactions.
• Ligand Synthesis for Catalysis: Serves as a precursor for synthesizing sophisticated ligands used in asymmetric catalysis and transition metal complexes.
• Academic & Contract Research: A valuable compound for universities and CROs (Contract Research Organizations) conducting fundamental research in synthetic methodology and heterocyclic chemistry.

Basic Information

Product Name	2,7-Diazaspiro[4.5]Decan-1-One
CAS No.	887118-43-6
Molecular Formula	C8H14N2O
Molecular Weight	154.21 g/mol
Synonyms	1-Oxa-4,9-diazaspiro[5.5]undecan-2-one; 2,7-Diazaspiro[4.5]decan-1-one; 1-Oxa-4,9-diazaspiro[5.5]undecan-2-one; Spirocyclic lactam intermediate; Diazaspirodecanone; 1-Oxa-4,9-diazaspiro[5.5]undecane-2-one
EINECS	Contact for details

Quality Control

Our 2,7-Diazaspiro[4.5]Decan-1-One is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, essential for sensitive R&D and scale-up processes. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay purity and impurity profiles. Our quality systems are designed to support cGMP (current Good Manufacturing Practice) compliance for pharmaceutical applications, and we can tailor specifications to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Purity (HPLC, Area %)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.