Description

1,4-Diazaspiro[5.5]undecane-1-carboxylic acid 1,1-dimethylethyl ester is a high-value, protected spirocyclic amine building block used in advanced organic synthesis. This compound is critical for medicinal chemistry research, enabling the construction of complex molecular architectures with precise stereochemistry. It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers developing novel active pharmaceutical ingredients (APIs) and other sophisticated organic molecules.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to introduce a rigid, spirocyclic amine moiety into molecular scaffolds.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands and organocatalysts used in asymmetric synthesis.
• Peptidomimetic Synthesis: Incorporated into the design of peptide mimics to enhance metabolic stability and bioavailability.
• Agrochemical Research: Employed in the development of novel, high-performance crop protection agents with specific biological activity.
• Academic & Industrial R&D: A valuable reagent for exploring new synthetic methodologies and constructing diverse chemical libraries for screening.

Basic Information

Product Name	1,4-Diazaspiro[5.5]undecane-1-carboxylic acid 1,1-dimethylethyl ester
CAS No.	886766-48-9
Molecular Formula	C14H26N2O2
Molecular Weight	254.37 g/mol
Synonyms	tert-Butyl 1,4-diazaspiro[5.5]undecane-1-carboxylate; 1,4-Diazaspiro[5.5]undecane-1-carboxylic acid tert-butyl ester; 1-Boc-1,4-diazaspiro[5.5]undecane; 1-N-Boc-1,4-diazaspiro[5.5]undecane; Boc-1,4-diazaspiro[5.5]undecane; 1-(tert-Butoxycarbonyl)-1,4-diazaspiro[5.5]undecane
EINECS	Contact for details

Quality Control

Our production of 1,4-Diazaspiro[5.5]undecane-1-carboxylic acid 1,1-dimethylethyl ester adheres to stringent quality management systems to ensure batch-to-batch consistency and high purity for research and development applications. All materials are characterized using advanced analytical techniques including NMR, HPLC, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect product stability and performance. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.