Description

4,7-Diaza-Spiro[2.5]Octane-7-Carboxylic Acid tert-Butyl Ester is a high-value, spirocyclic building block of significant interest in advanced organic synthesis. Its unique constrained bicyclic structure makes it a critical intermediate for constructing complex molecular architectures, particularly in pharmaceutical research and development. This compound is primarily sought after by medicinal chemists and process development scientists working on novel active pharmaceutical ingredients (APIs), especially within the fields of central nervous system (CNS) and metabolic disease therapeutics.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting neurological disorders.
• Medicinal Chemistry: Used in scaffold hopping and fragment-based drug design (FBDD) to explore new chemical space and improve drug-like properties.
• Chemical Biology: Serves as a precursor for synthesizing specialized probes and ligands for studying biological targets and pathways.
• Agrochemical Research: Employed in the development of new active ingredients with novel modes of action.
• Material Science: Potential use as a monomer or cross-linker in the development of specialty polymers with specific mechanical or optical properties.

Basic Information

Product Name	4,7-Diaza-Spiro[2.5]Octane-7-Carboxylic Acid tert-Butyl Ester
CAS No.	886766-28-5
Molecular Formula	C12H22N2O2
Molecular Weight	226.32 g/mol
Synonyms	tert-Butyl 4,7-diaza-spiro[2.5]octane-7-carboxylate; 7-(tert-Butoxycarbonyl)-4,7-diaza-spiro[2.5]octane; 4,7-Diaza-spiro[2.5]octane-7-carboxylic acid 1,1-dimethylethyl ester; Boc-4,7-Diaza-spiro[2.5]octane; 4,7-Diaza-spiro[2.5]octane, 7-Boc-protected; 886766-28-5; 4,7-Diaza-spiro[2.5]octane-7-carboxylic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our production of 4,7-Diaza-Spiro[2.5]Octane-7-Carboxylic Acid tert-Butyl Ester adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity, essential for sensitive pharmaceutical applications. Each lot is fully characterized and tested against rigorous internal specifications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This compound may be moisture-sensitive; keep the container tightly sealed under an inert atmosphere for long-term storage to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.