Description

5-Chloro-6-Oxo-1-(4-(Trifluoromethyl)Benzyl)-1,6-Dihydropyridine-3-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its distinct pyridine carboxylic acid core and trifluoromethyl benzyl substituent. This compound matters for its critical role as a sophisticated building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular design. It is primarily needed by research institutions and pharmaceutical manufacturers engaged in the development of new chemical entities, especially for applications in medicinal chemistry and process research.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the research and development of new Active Pharmaceutical Ingredients (APIs).
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies for novel drug candidates.
• Process Chemistry Development: Employed in route scouting and scale-up synthesis for pharmaceutical manufacturing processes.
• Chemical Biology Probes: Utilized in the synthesis of specialized molecules for target identification and validation in biological systems.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs producing bespoke compounds for clients.

Basic Information

Product Name	5-Chloro-6-Oxo-1-(4-(Trifluoromethyl)Benzyl)-1,6-Dihydropyridine-3-Carboxylic Acid
CAS No.	886761-94-0
Molecular Formula	C14H9ClF3NO3
Molecular Weight	331.67 g/mol
Synonyms	5-Chloro-1-[(4-trifluoromethyl)benzyl]-6-oxo-1,6-dihydropyridine-3-carboxylic acid; 1-(4-(Trifluoromethyl)benzyl)-5-chloro-6-oxo-1,6-dihydropyridine-3-carboxylic acid; 5-Chloro-6-oxo-1-[4-(trifluoromethyl)benzyl]-1,6-dihydropyridine-3-carboxylic acid; 886761-94-0; 5-Chloro-1-(4-trifluoromethylbenzyl)-6-oxo-1,6-dihydropyridine-3-carboxylic acid; 3-Pyridinecarboxylic acid, 5-chloro-1-[[4-(trifluoromethyl)phenyl]methyl]-1,6-dihydro-6-oxo-
EINECS	Contact for details

Quality Control

Our 5-Chloro-6-Oxo-1-(4-(Trifluoromethyl)Benzyl)-1,6-Dihydropyridine-3-Carboxylic Acid is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the stringent requirements for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity (typically ≥95% by HPLC), related substances, and other critical parameters is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic (moisture-sensitive); therefore, the container should be kept tightly sealed when not in use to minimize exposure to atmospheric humidity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.