Description

8-Methyl-1,4-Dioxaspiro[4.5]Decan-8-Amine is a specialized spirocyclic amine derivative, valued as a crucial chiral building block and intermediate in advanced organic synthesis. Its unique spirocyclic structure with a protected amine functionality makes it particularly significant for constructing complex molecular architectures with precise stereochemistry. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to develop novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and antiviral drug candidates.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where its spirocyclic structure contributes to biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for creating novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Fine Chemical Production: Employed in the synthesis of complex fragrance molecules, dyes, and other high-value specialty chemicals.
• Academic and R&D: A valuable compound for methodological studies in organic chemistry, particularly in ring-forming reactions and stereoselective transformations.
• Material Science Precursor: Potential use in the synthesis of monomers for specialized polymers or as a modifying agent for surface chemistry.

Basic Information

Product Name	8-Methyl-1,4-Dioxaspiro[4.5]Decan-8-Amine
CAS No.	886615-92-5
Molecular Formula	C9H17NO2
Molecular Weight	171.24 g/mol
Synonyms	8-Methyl-1,4-dioxaspiro[4.5]decan-8-amine; 8-Amino-8-methyl-1,4-dioxaspiro[4.5]decane; 8-Methyl-1,4-dioxaspiro[4.5]decan-8-ylamine; Spiro[1,3-dioxolane-2,1'-cyclohexan]-8-amine, 8-methyl-; 8-Methyl-1,4-dioxaspiro[4.5]decan-8-amine hydrochloride (salt form); 8-Methyl-1,4-dioxaspiro[4.5]decan-8-amine HBr (salt form)
EINECS	Contact for details

Quality Control

Our 8-Methyl-1,4-Dioxaspiro[4.5]Decan-8-Amine is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chromatography (HPLC, GC) and spectroscopic methods (NMR, IR), to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment ensures the material meets the high standards required for research and cGMP manufacturing applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Specific Rotation [α] (if chiral)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.