Description

2-[2-(Trifluoromethyl)Phenyl]Pyridin-3-Amine is a high-purity, advanced pharmaceutical intermediate characterized by its pyridine core and trifluoromethylphenyl substitution, which imparts unique electronic and steric properties. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted bioactivity and metabolic stability. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and material science industries for developing next-generation small-molecule drugs and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, especially in oncology, CNS disorders, and anti-inflammatory therapies.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging the trifluoromethyl group for enhanced lipophilicity and biological activity.
• Material Science Precursor: Serves as a monomer or functionalizing agent in the creation of advanced polymers, liquid crystals, or organic electronic materials.
• Chemical Synthesis: Acts as a versatile reagent in organic synthesis for constructing complex heterocyclic frameworks via cross-coupling and amination reactions.
• Academic & R&D: Employed in university and corporate research laboratories for methodological studies and exploring new chemical spaces.

Basic Information

Product Name	2-[2-(Trifluoromethyl)Phenyl]Pyridin-3-Amine
CAS No.	886507-97-7
Molecular Formula	C12H9F3N2
Molecular Weight	238.21 g/mol
Synonyms	3-Amino-2-[2-(trifluoromethyl)phenyl]pyridine; 2-(2-Trifluoromethylphenyl)pyridin-3-amine; 2-(α,α,α-Trifluoro-o-tolyl)-3-aminopyridine; 3-Pyridinamine, 2-[2-(trifluoromethyl)phenyl]-; 886507-97-7; 2-(2-Trifluoromethylphenyl)-3-pyridinamine
EINECS	Contact for details

Quality Control

Our 2-[2-(Trifluoromethyl)Phenyl]Pyridin-3-Amine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, confirming compliance with customer specifications and relevant industry guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials. The product is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.