Description

1-(2-Pyridin-4-Yl-Ethyl)-Piperidine-3-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate featuring a unique molecular scaffold that combines piperidine and pyridine moieties. This compound is of significant value for its role as a critical building block in the research and development of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and other therapeutic areas. It is primarily sought after by pharmaceutical R&D laboratories, custom synthesis providers, and agrochemical innovators for constructing complex molecules with targeted biological activity. The compound, identified by CAS number 886506-27-0, is supplied under stringent quality control to ensure batch-to-batch consistency for sensitive synthetic applications.

Application

• Pharmaceutical Intermediate: A key synthon in the multi-step synthesis of potential drug candidates, especially those targeting neurological receptors.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and library synthesis for hit-to-lead optimization.
• Agrochemical Development: Serves as a precursor in the creation of novel pesticides or herbicides that require complex heterocyclic architectures.
• Ligand Synthesis: Employed in the development of specialized ligands for catalysis or diagnostic imaging agents.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of client-specific target molecules.
• Academic Research: Utilized in university and institutional labs for exploratory organic synthesis and methodological studies.

Basic Information

Product Name	1-(2-Pyridin-4-Yl-Ethyl)-Piperidine-3-Carboxylic Acid
CAS No.	886506-27-0
Molecular Formula	C13H18N2O2
Molecular Weight	234.30 g/mol
Synonyms	3-Piperidinecarboxylic acid, 1-[2-(4-pyridinyl)ethyl]-; 1-[2-(Pyridin-4-yl)ethyl]piperidine-3-carboxylic acid; 1-(2-(4-Pyridyl)ethyl)nipecotic acid; Nipecotic acid, 1-[2-(4-pyridinyl)ethyl]-; 886506-27-0; 1-(4-Pyridin-2-ylethyl)piperidine-3-carboxylic acid (isomer); 1-(2-Pyridin-4-ylethyl)piperidine-3-carboxylic acid
EINECS	Contact for details

Quality Control

Our 1-(2-Pyridin-4-Yl-Ethyl)-Piperidine-3-Carboxylic Acid is manufactured under a quality management system and undergoes rigorous analytical testing to ensure it meets the high standards required for research and development applications. Each batch is characterized by HPLC, NMR, and mass spectrometry to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment to support your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.