Description

5-(3-Hydroxy-3-Methylbut-1-Yn-1-Yl)Nicotinic Acid (Saltdata: Free) is a high-purity, functionalized nicotinic acid derivative characterized by its unique alkyne-substituted side chain. This compound serves as a critical advanced pharmaceutical intermediate (API intermediate) and a versatile building block in organic synthesis. It is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for the development of novel active compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules, particularly those targeting neurological and metabolic pathways.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators due to its bioactive nicotinic acid core.
• Chemical Synthesis Building Block: The alkyne and hydroxyl functional groups make it a valuable reagent for click chemistry, cross-coupling reactions, and the construction of complex molecular architectures.
• Bioconjugation & Probe Development: Employed in biochemical research for labeling proteins, nucleic acids, and other biomolecules.
• Material Science Research: Investigated as a monomer or additive for creating functional polymers and advanced materials.

Basic Information

Product Name	5-(3-Hydroxy-3-Methylbut-1-Yn-1-Yl)Nicotinic Acid (Saltdata: Free)
CAS No.	886505-83-5
Molecular Formula	C11H11NO3
Molecular Weight	205.21 g/mol
Synonyms	5-(3-Hydroxy-3-methylbut-1-yn-1-yl)nicotinic acid; 3-Pyridinecarboxylic acid, 5-(3-hydroxy-3-methyl-1-butyn-1-yl)-; 5-(3-Hydroxy-3-methylbut-1-ynyl)nicotinic acid; 5-(3-Hydroxy-3-methylbutyn-1-yl)nicotinic acid; 5-(3-Hydroxy-3-methylbut-1-ynyl)pyridine-3-carboxylic acid; Nicotinic acid, 5-(3-hydroxy-3-methyl-1-butynyl)-
EINECS	Contact for details

Quality Control

Our production of 5-(3-Hydroxy-3-Methylbut-1-Yn-1-Yl)Nicotinic Acid adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical specifications are provided and available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under dry conditions to prevent product degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.