Description

3-(2,2-Dimethyl-[1,3]Dioxolan-4-Ylmethoxy)-4,4,4-Trifluoro-Butyric Acid Ethyl Ester is a high-value, specialized fluorinated organic intermediate. This compound is critical for its role in the synthesis of complex molecules, particularly in the pharmaceutical and agrochemical sectors, where the introduction of a trifluoromethyl group can dramatically alter biological activity and metabolic stability. It is an essential building block for research chemists and process development scientists working on novel active ingredients.

Application

This fluorinated ester serves as a versatile intermediate in advanced organic synthesis. Key application areas include:

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) containing trifluoromethyl motifs, which are prevalent in drugs for oncology, central nervous system (CNS) disorders, and metabolic diseases.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the fluorine atoms enhance lipophilicity, stability, and target binding.
• Material Science Research: Employed in the creation of fluorinated polymers and liquid crystals, contributing to unique material properties like chemical resistance and optical characteristics.
• Organic Chemistry Building Block: Utilized in academic and industrial R&D for constructing complex molecular architectures via reactions involving its ester and protected diol functional groups.

Basic Information

Item	Details
Product Name	3-(2,2-Dimethyl-[1,3]Dioxolan-4-Ylmethoxy)-4,4,4-Trifluoro-Butyric Acid Ethyl Ester
CAS No.	886505-47-1
Molecular Formula	C12H19F3O5
Molecular Weight	300.27 g/mol
Synonyms	Ethyl 3-(2,2-dimethyl-1,3-dioxolan-4-ylmethoxy)-4,4,4-trifluorobutanoate; 4,4,4-Trifluoro-3-[(2,2-dimethyl-1,3-dioxolan-4-yl)methoxy]butanoic Acid Ethyl Ester; 3-[(2,2-Dimethyl-1,3-dioxolan-4-yl)methoxy]-4,4,4-trifluorobutanoic Acid Ethyl Ester; 886505-47-1; Butanoic acid, 4,4,4-trifluoro-3-[(2,2-dimethyl-1,3-dioxolan-4-yl)methoxy]-, ethyl ester
EINECS	Contact for details

Quality Control

Our 3-(2,2-Dimethyl-[1,3]Dioxolan-4-Ylmethoxy)-4,4,4-Trifluoro-Butyric Acid Ethyl Ester is produced under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific customer or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.