Description

4-Pyridinecarbonitrile, 3-(4-Aminophenyl)-5-Chloro- is a high-value, multi-functional heterocyclic building block characterized by its pyridine core, nitrile group, and chlorinated aniline moiety. This compound matters for its role as a critical intermediate in the synthesis of advanced pharmaceutical agents and specialty organic materials, where its unique structure enables precise molecular modifications. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of kinase inhibitors, receptor antagonists, and other small-molecule drug candidates.
• Agrochemical Research: Building block for developing novel herbicides, fungicides, and plant growth regulators.
• Material Science: Used in the creation of advanced organic polymers, liquid crystals, and electronic materials.
• Chemical Synthesis: Serves as a versatile reagent for introducing the 3-(4-aminophenyl)-5-chloropyridine scaffold into more complex structures.
• Academic & Industrial R&D: Valuable compound for methodological studies and exploring new reaction pathways in organic chemistry.

Basic Information

Product Name	4-Pyridinecarbonitrile, 3-(4-Aminophenyl)-5-Chloro-
CAS No.	886457-32-5
Molecular Formula	C12H8ClN3
Molecular Weight	229.66 g/mol
Synonyms	3-(4-Aminophenyl)-5-chloro-4-pyridinecarbonitrile; 5-Chloro-3-(4-aminophenyl)isonicotinonitrile; 5-Chloro-3-(4-aminophenyl)pyridine-4-carbonitrile; 4-Cyano-5-chloro-3-(4-aminophenyl)pyridine; 886457-32-5; 3-(4-Aminophenyl)-5-chloroisonicotinonitrile
EINECS	Contact for details

Quality Control

Every batch of 4-Pyridinecarbonitrile, 3-(4-Aminophenyl)-5-Chloro- is produced and tested under a strict quality management system. We ensure compliance with high-purity standards suitable for research and development applications. Comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, is performed to verify identity, purity, and consistency. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its light-sensitive nature and propensity to be easily oxidized, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.