Description

4-Methyl-2-(2-Trifluoromethyl-Phenyl)-Pyridine is a specialized heterocyclic compound featuring a pyridine core substituted with a methyl group and a trifluoromethylphenyl moiety. This structure is highly valued for its role as a key synthetic intermediate in the development of advanced pharmaceutical and agrochemical products. It is primarily sought after by research and development chemists, process development scientists, and manufacturers in the life sciences sector for constructing complex molecules with targeted biological activity.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides, where the trifluoromethyl group can enhance metabolic stability and bioavailability.
• Material Science Precursor: Serves as a starting material for creating functionalized ligands used in catalysis and for synthesizing advanced organic electronic materials.
• Chemical Biology Probe: Employed in medicinal chemistry for structure-activity relationship (SAR) studies and as a scaffold for designing enzyme inhibitors or receptor modulators.

Basic Information

Product Name	4-Methyl-2-(2-Trifluoromethyl-Phenyl)-Pyridine
CAS No.	886444-13-9
Molecular Formula	C13H10F3N
Molecular Weight	237.22 g/mol
Synonyms	2-(2-(Trifluoromethyl)phenyl)-4-methylpyridine; 4-Methyl-2-[2-(trifluoromethyl)phenyl]pyridine; 2-(α,α,α-Trifluoro-o-tolyl)-4-picoline; 886444-13-9; 4-Methyl-2-(2-trifluoromethylphenyl)pyridine
EINECS	Contact for details

Quality Control

Our 4-Methyl-2-(2-Trifluoromethyl-Phenyl)-Pyridine is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring GMP-grade intermediates and research materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong bases and fluorides. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.