Description

Methyl 5-Amino-2-Chloropyridine-3-Carboxylate is a high-purity, multi-functional pyridine derivative serving as a critical building block in advanced organic synthesis. Its molecular structure, featuring both amino and chloro substituents, makes it an exceptionally versatile intermediate for constructing complex heterocyclic systems. This compound is essential for research and development chemists and process engineers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of various drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-infectives, and oncology therapies.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its pyridine core for biological activity.
• Ligand and Catalyst Development: Serves as a starting material for creating sophisticated chelating ligands and organocatalysts used in asymmetric synthesis and metal-catalyzed cross-coupling reactions.
• Material Science Research: Employed in the synthesis of organic semiconductors, liquid crystals, and photoactive compounds for electronic and optoelectronic applications.
• Custom Synthesis and Contract Manufacturing: A fundamental scaffold for custom chemical synthesis services, enabling the production of tailored molecules for specific client R&D projects.

Basic Information

Product Name	Methyl 5-Amino-2-Chloropyridine-3-Carboxylate
CAS No.	886435-73-0
Molecular Formula	C7H7ClN2O2
Molecular Weight	186.60 g/mol
Synonyms	5-Amino-2-chloro-3-pyridinecarboxylic acid methyl ester; Methyl 5-amino-2-chloronicotinate; 2-Chloro-5-aminonicotinic acid methyl ester; 3-Pyridinecarboxylic acid, 5-amino-2-chloro-, methyl ester; 886435-73-0; 5-Amino-2-chloro-pyridine-3-carboxylic acid methyl ester
EINECS	Contact for details

Quality Control

Every batch of Methyl 5-Amino-2-Chloropyridine-3-Carboxylate is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency meet the high standards required for synthetic applications. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.