Description

5-Chloro-3-Fluoro-2-Methoxy-Pyridine is a high-purity, multi-functional heterocyclic building block of significant importance in advanced organic synthesis. Its unique halogenated and methoxylated pyridine structure makes it a versatile intermediate for constructing complex molecules. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and central nervous system (CNS) drug discovery programs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, leveraging its halogenated pyridine core.
• Material Science Research: Serves as a precursor for the synthesis of functionalized ligands, organic electronic materials, and liquid crystals.
• Chemical Biology: Employed as a probe or labeling agent in medicinal chemistry and biochemical research due to its reactive halogen sites.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects and scale-up production under cGMP or ISO standards.

Basic Information

Product Name	5-Chloro-3-Fluoro-2-Methoxy-Pyridine
CAS No.	886374-01-2
Molecular Formula	C6H5ClFNO
Molecular Weight	161.56 g/mol
Synonyms	2-Methoxy-5-chloro-3-fluoropyridine; 3-Fluoro-5-chloro-2-methoxypyridine; 5-Chloro-3-fluoro-2-methoxypyridine; Pyridine, 5-chloro-3-fluoro-2-methoxy-; 886374-01-2
EINECS	Contact for details

Quality Control

Our 5-Chloro-3-Fluoro-2-Methoxy-Pyridine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data to support your regulatory and R&D requirements. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for every batch and provided upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Individual impurity ≤ 0.5%
Total Impurities	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.