Description

5-Chloro-2-Ethoxy-3-Fluoro-Pyridine is a high-purity, multi-functional pyridine derivative serving as a critical building block in advanced organic synthesis. Its unique halogenated and alkoxylated structure makes it an invaluable intermediate for constructing complex molecules with tailored properties. This compound is essential for research and development chemists and process engineers in the pharmaceutical and agrochemical industries, where it is used to develop new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and antiviral drug discovery programs.
• Agrochemical Synthesis: Used in the manufacture of advanced herbicides, fungicides, and insecticides, leveraging its halogenated pyridine core.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis and organocatalysis.
• Material Science Research: Building block for synthesizing functionalized polymers, liquid crystals, and electronic materials.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs and research institutions for bespoke chemical synthesis projects.

Basic Information

Product Name	5-Chloro-2-Ethoxy-3-Fluoro-Pyridine
CAS No.	886373-94-0
Molecular Formula	C7H7ClFNO
Molecular Weight	175.59 g/mol
Synonyms	3-Fluoro-5-chloro-2-ethoxypyridine; 2-Ethoxy-3-fluoro-5-chloropyridine; 5-Chloro-3-fluoro-2-ethoxypyridine; 886373-94-0; Pyridine, 5-chloro-2-ethoxy-3-fluoro-; 5-Chloro-2-ethoxy-3-fluoropyridine
EINECS	Contact for details

Quality Control

Every batch of 5-Chloro-2-Ethoxy-3-Fluoro-Pyridine is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to cGMP and ISO standards ensures reliable supply for your most demanding applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.