Description

5-Chloro-2-Ethoxypyridin-3-Amine is a versatile pyridine derivative building block of significant importance in advanced organic synthesis. Its value lies in its functionalized amine and chloro groups, which allow for selective derivatization to create complex molecular architectures. This compound is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drug candidates targeting central nervous system (CNS) disorders and infectious diseases.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, leveraging its heterocyclic core for bioactivity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the development of organic electronic materials, such as charge-transport layers or organic light-emitting diodes (OLEDs).
• Chemical Biology Probe: Utilized as a scaffold for developing molecular probes to study enzyme function and biological pathways.
• Custom Synthesis and Contract Manufacturing: A critical building block for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	5-Chloro-2-Ethoxypyridin-3-Amine
CAS No.	886373-74-6
Molecular Formula	C7H9ClN2O
Molecular Weight	172.61 g/mol
Synonyms	3-Amino-5-chloro-2-ethoxypyridine; 5-Chloro-2-ethoxy-3-pyridinamine; 2-Ethoxy-5-chloropyridin-3-amine; 886373-74-6; 5-Chloro-2-ethoxy-3-aminopyridine; 3-Pyridinamine, 5-chloro-2-ethoxy-; 5-Chloro-2-ethoxypyridin-3-ylamine
EINECS	Contact for details

Quality Control

Our 5-Chloro-2-Ethoxypyridin-3-Amine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We employ advanced analytical techniques, including HPLC, GC, NMR, and mass spectrometry, for comprehensive characterization and impurity profiling. Certificates of Analysis (COA) detailing purity, identity, and related substances are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.