Description

5-Chloro-2-Ethoxy-3-Nitropyridine is a high-purity, multi-functional heterocyclic building block of significant importance in advanced organic synthesis. Its core value lies in its versatile reactivity, primarily serving as a key intermediate for the development of complex molecules in the pharmaceutical and agrochemical sectors. This compound is essential for researchers and manufacturers engaged in creating active pharmaceutical ingredients (APIs), crop protection agents, and other fine chemicals.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and anti-infective agents.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides, leveraging its pyridine-based structure.
• Material Science Research: Serves as a building block for creating functionalized polymers, liquid crystals, and organic electronic materials.
• Chemical Biology & Proteomics: Employed in the design and synthesis of molecular probes, enzyme inhibitors, and bioconjugation reagents.
• Dye & Pigment Manufacturing: Acts as an intermediate for synthesizing specialized nitro- and chloro-substituted heterocyclic dyes.
• Cross-Coupling Reactions: A valuable substrate for palladium-catalyzed reactions like Suzuki, Stille, or Buchwald-Hartwig amination to create complex biaryl structures.

Basic Information

Product Name	5-Chloro-2-Ethoxy-3-Nitropyridine
CAS No.	886373-32-6
Molecular Formula	C7H7ClN2O3
Molecular Weight	202.60 g/mol
Synonyms	3-Nitro-5-chloro-2-ethoxypyridine; 2-Ethoxy-5-chloro-3-nitropyridine; 5-Chloro-2-ethoxy-3-nitro-pyridine; Pyridine, 5-chloro-2-ethoxy-3-nitro-; 886373-32-6; 5-Chloro-3-nitro-2-ethoxypyridine
EINECS	Contact for details

Quality Control

Our 5-Chloro-2-Ethoxy-3-Nitropyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistent performance. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Light yellow to yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.