Description

5-Bromo-3-Fluoro-Pyridine-2-Carbonitrile is a high-value, multi-functional heterocyclic building block essential for modern synthetic chemistry. Its unique halogenated pyridine core makes it a critical intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and CNS drug discovery programs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, leveraging its halogenated structure for bioactivity.
• Material Science Research: Serves as a precursor for functionalized ligands and organic electronic materials due to its electron-withdrawing nitrile and halogen groups.
• Cross-Coupling Reactions: The bromine atom is an excellent site for palladium-catalyzed reactions (e.g., Suzuki, Stille), enabling rapid diversification of the pyridine scaffold.
• Chemical Biology Probes: Utilized in the synthesis of molecular probes and tags for studying biological processes and target engagement.

Basic Information

Product Name	5-Bromo-3-Fluoro-Pyridine-2-Carbonitrile
CAS No.	886373-28-0
Molecular Formula	C6H2BrFN2
Molecular Weight	201.00 g/mol
Synonyms	2-Cyano-5-bromo-3-fluoropyridine; 3-Fluoro-5-bromopyridine-2-carbonitrile; 5-Bromo-3-fluoropicolinonitrile; 5-Bromo-3-fluoro-2-pyridinecarbonitrile; 886373-28-0; 2-Pyridinecarbonitrile, 5-bromo-3-fluoro-
EINECS	Contact for details

Quality Control

Our 5-Bromo-3-Fluoro-Pyridine-2-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the exacting standards required for advanced R&D and scale-up. Certificates of Analysis (COA) with full traceability are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.