Description

6-Bromo-Oxazolo[5,4-B]Pyridine is a high-value brominated heterocyclic building block, specifically an oxazolopyridine derivative, essential for advanced organic synthesis. Its core value lies in its role as a versatile and reactive intermediate for constructing complex molecular architectures, particularly in pharmaceutical research and development. This compound is primarily needed by medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the creation of novel herbicides, fungicides, and insecticides that require complex heterocyclic cores.
• Material Science Research: Serves as a building block for organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors.
• Chemical Biology Probes: Employed in the synthesis of labeled compounds and molecular probes for studying biological pathways and target engagement.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for palladium-catalyzed reactions like Suzuki, Sonogashira, and Buchwald-Hartwig couplings.
• Library Synthesis for HTS: A valuable scaffold for generating diverse compound libraries used in high-throughput screening (HTS) campaigns.

Basic Information

Product Name	6-Bromo-Oxazolo[5,4-B]Pyridine
CAS No.	886372-90-3
Molecular Formula	C6H3BrN2O
Molecular Weight	199.01 g/mol
Synonyms	6-Bromo[1,3]oxazolo[5,4-b]pyridine; 6-Bromooxazolo[5,4-b]pyridine; Oxazolo[5,4-b]pyridine, 6-bromo-; 886372-90-3; 6-Bromo-oxazolo[5,4-b]pyridine; 6-Bromo-1,3-oxazolo[5,4-b]pyridine
EINECS	Contact for details

Quality Control

Our 6-Bromo-Oxazolo[5,4-B]Pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and consistent performance. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your quality and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials. Due to its light-sensitive nature, handling and storage should minimize exposure to direct light.

Specification

Item	Specification
Appearance	White to off-white powder/crystals
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.