Description

5-Fluoro-6-Methoxy-Pyridin-3-Ylamine is a high-purity, versatile pyridine derivative building block essential for advanced organic synthesis. This compound matters for its role as a key intermediate in the development of active pharmaceutical ingredients (APIs) and agrochemicals, where its specific fluorine and methoxy substitution pattern enables precise molecular design. It is primarily needed by research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to create novel compounds with targeted biological activity.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel drug candidates, particularly in kinase inhibitor and central nervous system (CNS) active compound research.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, leveraging its heterocyclic structure for bioactivity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of organic electronic materials and functional dyes due to its electron-donating methoxy group.
• Custom Synthesis and Contract Manufacturing: A key starting material for custom synthesis projects and scale-up processes in fine chemical production.
• Academic and Industrial R&D: Used in medicinal chemistry labs for structure-activity relationship (SAR) studies and hit-to-lead optimization.

Basic Information

Product Name	5-Fluoro-6-Methoxy-Pyridin-3-Ylamine
CAS No.	886372-63-0
Molecular Formula	C6H7FN2O
Molecular Weight	142.13 g/mol
Synonyms	3-Amino-5-fluoro-6-methoxypyridine; 5-Fluoro-6-methoxy-3-pyridinamine; 5-Fluoro-6-methoxypyridin-3-amine; 6-Methoxy-5-fluoropyridin-3-amine; 3-Pyridinamine, 5-fluoro-6-methoxy-; 5-Fluoro-6-methoxy-3-aminopyridine
EINECS	Contact for details

Quality Control

Our 5-Fluoro-6-Methoxy-Pyridin-3-Ylamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure compliance with stringent industry standards. Certificates of Analysis (COA) detailing batch-specific results are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, long-term storage under an inert atmosphere (e.g., nitrogen or argon) is recommended for optimal stability. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.