Description

4-Bromo-2-Cyano-6-Methylpyridine is a versatile and high-purity halogenated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique molecular structure, featuring both bromo and cyano substituents, makes it an invaluable intermediate for constructing complex heterocyclic systems and functionalized molecules. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and material science industries, where it is used to develop new active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly for kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the development of advanced pesticides, herbicides, and fungicides due to its reactive halogen and nitrile functional groups.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and coordination chemistry.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as components for OLEDs or conductive polymers.
• Chemical Biology Probes: Useful for synthesizing tagged molecules and probes for studying biological processes and target engagement.
• Custom Synthesis and Scale-Up: A fundamental substrate for contract research organizations (CROs) and CDMOs performing custom synthesis from milligram to kilogram scale.

Basic Information

Product Name	4-Bromo-2-Cyano-6-Methylpyridine
CAS No.	886372-53-8
Molecular Formula	C7H5BrN2
Molecular Weight	197.04 g/mol
Synonyms	6-Methyl-4-bromopicolinonitrile; 4-Bromo-6-methylpicolinonitrile; 2-Cyano-4-bromo-6-methylpyridine; 4-Bromo-2-cyano-6-picoline; 4-Bromo-6-methyl-2-pyridinecarbonitrile; 2-Pyridinecarbonitrile, 4-bromo-6-methyl-
EINECS	Contact for details

Quality Control

Every batch of 4-Bromo-2-Cyano-6-Methylpyridine is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high standards required for research and commercial synthesis. Our products undergo rigorous quality testing, including HPLC, NMR, and GC-MS analysis, to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.