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tert-Butyl ((4-Aminopyridin-2-Yl)Methyl)Carbamate CAS NO 886371-80-8


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CAS No.:886371-80-8

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

tert-Butyl ((4-Aminopyridin-2-Yl)Methyl)Carbamate is a high-purity, protected amine derivative that serves as a critical building block in modern organic synthesis. Its primary value lies in enabling the controlled introduction of the 4-amino-2-methylpyridine moiety into complex molecular architectures, which is essential for developing novel active pharmaceutical ingredients. This compound is particularly vital for research and development chemists in the pharmaceutical and agrochemical industries who are engaged in the synthesis of new drug candidates and specialty chemicals.

Application

  • Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small molecule therapeutics.
  • Agrochemical Research: Used in the development of novel pesticides and herbicides, leveraging the pyridine core for biological activity.
  • Chemical Synthesis Building Block: The tert-butyloxycarbonyl (Boc) protecting group allows for selective reactions, making it invaluable for multi-step synthetic routes in medicinal chemistry.
  • Ligand and Catalyst Development: Serves as a starting material for creating complex ligands used in catalysis and material science.
  • Academic and R&D Laboratories: Employed in research institutions for exploring new chemical reactions and developing novel heterocyclic compounds.

Basic Information

Product Name tert-Butyl ((4-Aminopyridin-2-Yl)Methyl)Carbamate
CAS No. 886371-80-8
Molecular Formula C11H17N3O2
Molecular Weight 223.27 g/mol
Synonyms Boc-4-amino-2-picolylamine; tert-Butyl N-[(4-aminopyridin-2-yl)methyl]carbamate; 2-[[(tert-Butoxycarbonyl)amino]methyl]-4-aminopyridine; Carbamic acid, N-[(4-amino-2-pyridinyl)methyl]-, 1,1-dimethylethyl ester; (4-Amino-pyridin-2-ylmethyl)-carbamic acid tert-butyl ester; N-Boc-2-(aminomethyl)-4-aminopyridine
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Quality Control

Our tert-Butyl ((4-Aminopyridin-2-Yl)Methyl)Carbamate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere to prevent degradation. Keep away from strong oxidizing agents.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Identification (HPLC) Conforms to reference standard
Assay (HPLC) ≥ 98.0%
Water Content (KF) ≤ 0.5%
Residue on Ignition ≤ 0.1%
Heavy Metals ≤ 10 ppm
Single Unknown Impurity (HPLC) ≤ 0.5%
Total Impurities (HPLC) ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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