Description

5-Bromo-2-Trifluoromethoxy-Pyridine is a high-value halogenated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both bromine and trifluoromethoxy substituents, provides versatile reactivity for constructing complex molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to develop novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in kinase inhibitors and central nervous system (CNS) drugs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, leveraging the bioactivity of the pyridine core.
• Material Science: Serves as a precursor for functional materials, including liquid crystals and organic light-emitting diodes (OLEDs).
• Chemical Research: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic aromatic substitution to introduce complex functionalities.
• Fluorine Chemistry: The trifluoromethoxy group makes it a valuable scaffold for studying and incorporating fluorinated motifs, which are prized for their metabolic stability and lipophilicity.

Basic Information

Product Name	5-Bromo-2-Trifluoromethoxy-Pyridine
CAS No.	886371-77-3
Molecular Formula	C6H3BrF3NO
Molecular Weight	241.99 g/mol
Synonyms	2-Bromo-5-(trifluoromethoxy)pyridine; 5-Bromo-2-(trifluoromethoxy)pyridine; 2-(Trifluoromethoxy)-5-bromopyridine; Pyridine, 5-bromo-2-(trifluoromethoxy)-; 886371-77-3; 5-Br-2-OCF3-Pyridine
EINECS	Contact for details

Quality Control

Our 5-Bromo-2-Trifluoromethoxy-Pyridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with every shipment, detailing all relevant specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.