Description

2-(2-Bromo-5-Methyl-Thiazol-4-Yl)-Pyridine is a high-purity, advanced pharmaceutical intermediate with the CAS number 886370-92-9. This heterocyclic compound is a critical building block in modern medicinal chemistry, valued for its precise molecular architecture that enables the synthesis of complex active pharmaceutical ingredients (APIs). It is primarily sought by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of novel therapeutic agents and crop protection solutions.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in oncology and antiviral research.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, leveraging its thiazole-pyridine core.
• Chemical Research & Development: Serves as a versatile scaffold for medicinal chemists in structure-activity relationship (SAR) studies and hit-to-lead optimization.
• Material Science: Potential application as a ligand or building block for functional materials and coordination chemistry.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.

Basic Information

Product Name	2-(2-Bromo-5-Methyl-Thiazol-4-Yl)-Pyridine
CAS No.	886370-92-9
Molecular Formula	C9H7BrN2S
Molecular Weight	255.13 g/mol
Synonyms	2-(2-Bromo-5-methyl-1,3-thiazol-4-yl)pyridine; 4-Pyridin-2-yl-2-bromo-5-methyl-1,3-thiazole; 2-Bromo-5-methyl-4-(pyridin-2-yl)thiazole; 2-Bromo-5-methyl-4-(2-pyridinyl)thiazole; 886370-92-9; 2-(2-Bromo-5-methylthiazol-4-yl)pyridine
EINECS	Contact for details

Quality Control

Our production of 2-(2-Bromo-5-Methyl-Thiazol-4-Yl)-Pyridine adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) for every shipment, supporting compliance with cGMP and ICH Q7 guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat sources and incompatible materials. The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.