Description

2-(4-Bromo-2-Methyl-Phenyl)-Thiazole-4-Carboxylic Acid Ethyl Ester is a high-purity, synthetically valuable heterocyclic building block used in advanced organic synthesis. This compound matters for its role as a critical intermediate in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily needed by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-inflammatory agents, and kinase inhibitors.
• Agrochemical Research: Serves as a core scaffold for developing new-generation herbicides, fungicides, and insecticides with improved efficacy and selectivity.
• Material Science: Used in the research and development of organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors, due to its conjugated thiazole system.
• Chemical Biology: Employed as a molecular probe or tag in biochemical research to study enzyme interactions and cellular pathways.
• Custom Synthesis: Provides a versatile starting point for contract research organizations (CROs) and fine chemical manufacturers to produce bespoke compounds for client projects.
• Academic Research: Utilized in university and institutional laboratories for methodological development in heterocyclic and cross-coupling chemistry.

Basic Information

Product Name	2-(4-Bromo-2-Methyl-Phenyl)-Thiazole-4-Carboxylic Acid Ethyl Ester
CAS No.	886368-25-8
Molecular Formula	C13H12BrNO2S
Molecular Weight	326.21 g/mol
Synonyms	Ethyl 2-(4-bromo-2-methylphenyl)thiazole-4-carboxylate; 2-(4-Bromo-2-methylphenyl)-4-thiazolecarboxylic acid ethyl ester; 4-Carbethoxy-2-(4-bromo-2-methylphenyl)thiazole; 886368-25-8; 2-(4-Bromo-o-tolyl)-1,3-thiazole-4-carboxylic acid ethyl ester; 2-(4-Bromo-2-methylphenyl)-1,3-thiazole-4-carboxylic acid ethyl ester; Ethyl 2-(4-bromo-2-methylphenyl)-1,3-thiazole-4-carboxylate
EINECS	Contact for details

Quality Control

Our 2-(4-Bromo-2-Methyl-Phenyl)-Thiazole-4-Carboxylic Acid Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our commitment to supply chain integrity and documentation traceability meets the stringent requirements of pharmaceutical and advanced chemical industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound is light-sensitive (store away from light) and should be handled under inert atmosphere when appropriate for prolonged use. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.