Description

Methyl 2-n-Boc-2-Aminomethyl-3-(3-Chloro-Phenyl)-Propionate is a protected amino acid ester derivative, serving as a crucial chiral building block in advanced organic synthesis. This compound is valued for its role in constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and bioactive peptides. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in medicinal chemistry and process development.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and antiviral research.
• Peptidomimetics Construction: Used to incorporate non-natural amino acid residues into peptide backbones to enhance stability and biological activity.
• Chemical Biology Research: Employed in the development of molecular probes and enzyme inhibitors for target validation studies.
• Process Chemistry: Serves as a starting material or intermediate in the scalable, multi-step synthesis of complex organic molecules under GMP conditions.
• Custom Synthesis: Provides a versatile scaffold for contract research organizations (CROs) and CDMOs to build bespoke compounds for client projects.

Basic Information

Item	Details
Product Name	Methyl 2-n-Boc-2-Aminomethyl-3-(3-Chloro-Phenyl)-Propionate
CAS No.	886366-55-8
Molecular Formula	C17H24ClNO4
Molecular Weight	341.83 g/mol
Synonyms	Methyl 2-((tert-butoxycarbonyl)aminomethyl)-3-(3-chlorophenyl)propanoate; Boc-3-(3-Cl-Phe)-OMe; (R/S)-Methyl 2-(Boc-aminomethyl)-3-(3-chlorophenyl)propionate; 2-((tert-Butoxycarbonyl)amino)methyl-3-(3-chlorophenyl)propionic acid methyl ester; 886366-55-8; tert-Butyl N-[(2-methoxy-2-oxo-1-(3-chlorobenzyl)ethyl]carbamate
EINECS	Contact for details

Quality Control

Our Methyl 2-n-Boc-2-Aminomethyl-3-(3-Chloro-Phenyl)-Propionate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity and impurity profile analysis by HPLC, to ensure it meets the high standards required for pharmaceutical R&D. A Certificate of Analysis (COA) detailing identity, purity, and specific tests is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as specified on the label or COA. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (or as specified)
Related Substances (HPLC)	Individual impurity ≤ 0.5%
Total Impurities	≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.