Description

1-(6-Chloro-Pyridin-3-Yl)-2-Methyl-3-(4-Boc-Piperazin-1-Yl)-Propan-1-One is a high-purity, advanced pharmaceutical intermediate featuring a unique molecular scaffold combining pyridine and piperazine functionalities. This compound is critical for research and development in medicinal chemistry, particularly for constructing complex molecules with targeted biological activity. It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers engaged in the synthesis of novel active pharmaceutical ingredients (APIs) and drug candidates.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and oncology research.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization due to its versatile Boc-protected piperazine moiety.
• Custom Synthesis: Serves as a starting material or intermediate for contract research organizations (CROs) and CDMOs developing proprietary compounds.
• Chemical Biology Probes: Utilized in the development of chemical probes for studying biological pathways and target validation.
• Library Synthesis: An important component for generating diverse compound libraries for high-throughput screening (HTS).
• Process Chemistry Development: Employed in scaling up synthetic routes for potential Active Pharmaceutical Ingredients (APIs).

Basic Information

Product Name	1-(6-Chloro-Pyridin-3-Yl)-2-Methyl-3-(4-Boc-Piperazin-1-Yl)-Propan-1-One
CAS No.	886365-66-8
Molecular Formula	C18H26ClN3O3
Molecular Weight	367.87 g/mol
Synonyms	1-(6-Chloro-3-pyridinyl)-2-methyl-3-[4-[(1,1-dimethylethoxy)carbonyl]-1-piperazinyl]-1-propanone; 1-(6-Chloropyridin-3-yl)-2-methyl-3-(4-Boc-piperazin-1-yl)propan-1-one; tert-Butyl 4-[3-(6-chloropyridin-3-yl)-2-methyl-3-oxopropyl]piperazine-1-carboxylate; 886365-66-8; 1-Propanone, 1-(6-chloro-3-pyridinyl)-2-methyl-3-[4-[(1,1-dimethylethoxy)carbonyl]-1-piperazinyl]-; 3-(4-(tert-Butoxycarbonyl)piperazin-1-yl)-1-(6-chloropyridin-3-yl)-2-methylpropan-1-one
EINECS	Contact for details

Quality Control

Our production of 1-(6-Chloro-Pyridin-3-Yl)-2-Methyl-3-(4-Boc-Piperazin-1-Yl)-Propan-1-One adheres to stringent quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure compliance with research-grade and pharmaceutical intermediate standards. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment to guarantee traceability and consistency for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The container should be kept tightly sealed in a dry environment to minimize exposure to moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Individual impurity ≤ 1.0%
Total Impurities	≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.