Description

5-Bromo-2-Pyrrolidin-2-Yl-Pyridine is a high-value brominated heterocyclic compound featuring a fused pyridine-pyrrolidine structure, serving as a critical building block in advanced organic synthesis. This compound is prized for its role as a versatile intermediate in the development of complex molecules, particularly in pharmaceutical research and agrochemical discovery. It is essential for medicinal chemists and R&D professionals engaged in creating novel active ingredients, where its unique scaffold enables the exploration of new chemical space and the modulation of biological activity.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, especially for central nervous system (CNS) targets and kinase inhibitors.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its heterocyclic core for bioactivity.
• Ligand Synthesis: Employed in the creation of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Serves as a scaffold for designing molecular probes to study enzyme function and biological pathways.
• Material Science: A building block for organic electronic materials and advanced polymers requiring specific bromine functionality for further coupling reactions.

Basic Information

Product Name	5-Bromo-2-Pyrrolidin-2-Yl-Pyridine
CAS No.	886365-48-6
Molecular Formula	C9H11BrN2
Molecular Weight	227.10 g/mol
Synonyms	5-Bromo-2-(pyrrolidin-2-yl)pyridine; 2-(5-Bromopyridin-2-yl)pyrrolidine; 5-Bromo-2-pyrrolidin-2-ylpyridine; 886365-48-6; 5-Bromo-2-(2-pyrrolidinyl)pyridine; Pyrrolidine, 2-(5-bromo-2-pyridinyl)-; 5-Bromo-2-pyrrolidin-2-yl-pyridine
EINECS	Contact for details

Quality Control

Our 5-Bromo-2-Pyrrolidin-2-Yl-Pyridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting all critical parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most demanding R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability. Keep away from strong acids and incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥97.0%
Related Substances (HPLC)	Total impurities ≤3.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.