Description

1-(5-Bromo-2-Chloropyridin-3-Yl)Ethanone is a high-purity halogenated pyridine derivative serving as a critical building block in advanced organic synthesis. This compound matters for its role as a versatile intermediate, enabling the construction of complex molecular architectures with precise regiochemistry. Pharmaceutical, agrochemical, and material science researchers need it for developing new active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and antiviral drug discovery programs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, leveraging its halogenated pyridine core.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis and organocatalysis.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as charge-transport layers and light-emitting components.
• Chemical Biology Probes: Utilized as a scaffold for designing molecular probes and tags to study biological systems and pathways.
• Custom Synthesis and Contract Manufacturing: A fundamental starting material for custom synthesis services catering to R&D and pilot-scale production.

Basic Information

Product Name	1-(5-Bromo-2-Chloropyridin-3-Yl)Ethanone
CAS No.	886365-47-5
Molecular Formula	C7H5BrClNO
Molecular Weight	234.48 g/mol
Synonyms	5-Bromo-2-chloro-3-acetylpyridine; 3-Acetyl-5-bromo-2-chloropyridine; 1-(5-Bromo-2-chloro-3-pyridinyl)ethanone; Ethanone, 1-(5-bromo-2-chloro-3-pyridinyl)-; 886365-47-5; 5-Bromo-2-chloropyridin-3-yl methyl ketone
EINECS	Contact for details

Quality Control

Our 1-(5-Bromo-2-Chloropyridin-3-Yl)Ethanone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports applications requiring high-purity intermediates under cGMP and ISO guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The compound is light-sensitive and should be handled under an inert atmosphere for prolonged procedures to minimize degradation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Any single impurity	≤0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.