Description

5-Chloro-3-Methyl-Pyridine-2-Carboxylic Acid is a high-purity, versatile pyridine derivative serving as a critical building block in advanced organic synthesis. This compound is essential for the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where its unique halogenated and carboxylated structure enables precise molecular modifications. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of complex drug molecules, particularly in developing kinase inhibitors, antiviral agents, and other bioactive compounds.
• Agrochemical Synthesis: Used in the research and production of modern pesticides, herbicides, and fungicides, leveraging its halogenated pyridine core.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in metal-catalyzed cross-coupling reactions and other catalytic processes.
• Material Science Research: Employed in the synthesis of functionalized organic materials and metal-organic frameworks (MOFs) for specialized applications.
• Chemical Reference Standard: Supplied as a high-purity standard for analytical method development, validation, and quality control in regulatory testing.

Basic Information

Product Name	5-Chloro-3-Methyl-Pyridine-2-Carboxylic Acid
CAS No.	886365-46-4
Molecular Formula	C7H6ClNO2
Molecular Weight	171.58 g/mol
Synonyms	2-Pyridinecarboxylic acid, 5-chloro-3-methyl-; 5-Chloro-3-methylpicolinic acid; 3-Methyl-5-chloropicolinic acid; 5-Chloro-3-methyl-2-pyridinecarboxylic acid; 5-Chloro-3-methyl-pyridine-2-carboxylic acid; 886365-46-4; 5-Chloro-3-methylpicolinate
EINECS	Contact for details

Quality Control

Our 5-Chloro-3-Methyl-Pyridine-2-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, supporting its use in regulated research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible materials. For long-term storage, consider inert gas purging to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.