Description

5-Bromo-2-Methoxy-Isonicotinic Acid Methyl Ester is a high-purity, multi-functional chemical building block essential for advanced organic synthesis. This compound is valued for its unique halogenated and methoxylated pyridine core, which facilitates complex molecular transformations. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders and infectious diseases.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging its halogenated heterocyclic structure.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in metal-catalyzed cross-coupling reactions.
• Material Science Research: Employed in the development of organic electronic materials and advanced polymers due to its functionalized aromatic system.
• Custom Synthesis & Contract Manufacturing: A critical building block for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.
• Academic & Industrial R&D: Used in research laboratories for methodological studies and the exploration of new chemical spaces in medicinal and synthetic chemistry.

Basic Information

Item	Details
Product Name	5-Bromo-2-Methoxy-Isonicotinic Acid Methyl Ester
CAS No.	886365-25-9
Molecular Formula	C8H8BrNO3
Molecular Weight	246.06 g/mol
Synonyms	Methyl 5-bromo-2-methoxyisonicotinate; 5-Bromo-2-methoxypyridine-4-carboxylic acid methyl ester; 4-Pyridinecarboxylic acid, 5-bromo-2-methoxy-, methyl ester; 5-Bromo-2-methoxy-4-pyridinecarboxylic acid methyl ester; 886365-25-9; Methyl 5-bromo-2-methoxypyridine-4-carboxylate
EINECS	Contact for details

Quality Control

Our 5-Bromo-2-Methoxy-Isonicotinic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases and incompatible organic solvents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.