Description

5-Chloro-4-Methyl-Pyridine-2-Carboxylic Acid is a high-value pyridine derivative that serves as a critical synthetic intermediate in advanced organic chemistry. Its unique substitution pattern makes it an essential building block for constructing complex molecules with tailored properties. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for drug discovery programs targeting neurological and metabolic disorders.
• Agrochemical Synthesis: Building block for developing new generation herbicides, fungicides, and insecticides with improved efficacy and environmental profiles.
• Ligand and Catalyst Development: Used to create sophisticated chelating ligands and organocatalysts for asymmetric synthesis and metal complexation.
• Material Science Research: Intermediate for synthesizing functionalized polymers, liquid crystals, and organic electronic materials.
• Chemical Biology Probes: Serves as a core structure for designing molecular probes and inhibitors for studying enzyme function and biological pathways.

Basic Information

Product Name	5-Chloro-4-Methyl-Pyridine-2-Carboxylic Acid
CAS No.	886365-04-4
Molecular Formula	C7H6ClNO2
Molecular Weight	171.58 g/mol
Synonyms	2-Pyridinecarboxylic acid, 5-chloro-4-methyl-; 5-Chloro-4-methylpicolinic acid; 4-Methyl-5-chloropyridine-2-carboxylic acid; 5-Chloro-4-methyl-2-pyridinecarboxylic acid; 5-Chloro-4-methylpicolinate; Picolinic acid, 5-chloro-4-methyl-; 886365-04-4
EINECS	Contact for details

Quality Control

Our production of 5-Chloro-4-Methyl-Pyridine-2-Carboxylic Acid adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is fully characterized and tested against rigorous in-house specifications using advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment. We support cGMP compliance for pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment. Keep away from strong bases and strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.