Description

5-Bromo-4-Methyl-Pyridine-2-Carbonitrile is a high-purity, multi-functional heterocyclic building block essential for advanced organic synthesis. Its core value lies in its versatile reactivity, serving as a key precursor for constructing complex molecular architectures in pharmaceutical and agrochemical research. This compound is critically needed by R&D chemists and process development scientists in the fine chemical, pharmaceutical, and agrochemical industries for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and central nervous system (CNS) drug discovery programs.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging the pyridine core for bioactivity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as components for OLEDs or conductive polymers, due to its electron-deficient pyridine ring.
• Chemical Biology Probes: Utilized as a scaffold for developing molecular probes and tags to study biological processes and enzyme functions.
• Custom Synthesis and Contract Manufacturing: A key starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	5-Bromo-4-Methyl-Pyridine-2-Carbonitrile
CAS No.	886364-86-9
Molecular Formula	C7H5BrN2
Molecular Weight	197.04 g/mol
Synonyms	5-Bromo-4-methylpicolinonitrile; 2-Cyano-5-bromo-4-methylpyridine; 4-Methyl-5-bromopyridine-2-carbonitrile; 5-Bromo-4-methyl-2-pyridinecarbonitrile; 5-Bromo-4-methyl-2-cyanopyridine; 2-Pyridinecarbonitrile, 5-bromo-4-methyl-; 886364-86-9
EINECS	Contact for details

Quality Control

Our 5-Bromo-4-Methyl-Pyridine-2-Carbonitrile is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Our quality commitment ensures reliable performance in your most sensitive synthetic applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.