Description

1-(6-Bromopyridin-2-Yl)-2,2,2-Trifluoroethanone is a high-value brominated and fluorinated pyridine derivative, serving as a critical synthetic intermediate. Its molecular architecture, featuring both a reactive bromine atom and an electron-withdrawing trifluoroacetyl group, makes it an indispensable building block for constructing complex molecules. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides, where the bromopyridine moiety contributes to biological activity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and cross-coupling reactions.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as ligands for OLEDs or molecular semiconductors.
• Custom Synthesis and Contract Manufacturing: A vital substrate for fine chemical and custom synthesis houses serving the life sciences industry.
• Academic and R&D Laboratories: Used in medicinal chemistry programs for structure-activity relationship (SAR) studies and library synthesis.

Basic Information

Item	Details
Product Name	1-(6-Bromopyridin-2-Yl)-2,2,2-Trifluoroethanone
CAS No.	886364-57-4
Molecular Formula	C7H3BrF3NO
Molecular Weight	253.00 g/mol
Synonyms	2,2,2-Trifluoro-1-(6-bromopyridin-2-yl)ethanone; 1-(6-Bromo-2-pyridinyl)-2,2,2-trifluoroethanone; 6-Bromo-2-pyridyl trifluoromethyl ketone; 6-Bromo-2-trifluoroacetylpyridine; 2-Acetyl-6-bromopyridine trifluoromethyl ketone; 2-(Trifluoroacetyl)-6-bromopyridine; (6-Bromopyridin-2-yl)(trifluoro)methanone
EINECS	Contact for details

Quality Control

Every batch of 1-(6-Bromopyridin-2-Yl)-2,2,2-Trifluoroethanone is manufactured under a strict quality management system. We provide comprehensive analytical documentation, including a Certificate of Analysis (COA) detailing purity, identity, and impurity profiles verified by HPLC, GC, NMR, and IR spectroscopy. Our quality commitment ensures the material meets the stringent requirements for advanced R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong acids and bases. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.