Description

1-(5-Bromo-2-Pyridinyl)-2,2,2-Trifluoroethanone is a high-purity, advanced pharmaceutical intermediate characterized by its bromopyridine and trifluoroacetyl functional groups. This compound is essential for synthesizing novel active pharmaceutical ingredients (APIs) and agrochemicals, where its unique structure enables precise molecular modifications. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for drug discovery and process development.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly in medicinal chemistry research.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides due to its bioactive pyridine core.
• Ligand and Catalyst Preparation: Serves as a precursor for creating specialized ligands in catalytic systems and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the development of organic electronic materials and fluorinated polymers.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom chemical production.

Basic Information

Product Name	1-(5-Bromo-2-Pyridinyl)-2,2,2-Trifluoroethanone
CAS No.	886364-50-7
Molecular Formula	C7H3BrF3NO
Molecular Weight	253.00 g/mol
Synonyms	5-Bromo-2-(trifluoroacetyl)pyridine; 2,2,2-Trifluoro-1-(5-bromo-2-pyridinyl)ethanone; 1-(5-Bromopyridin-2-yl)-2,2,2-trifluoroethanone; 5-Bromo-α,α,α-trifluoro-2-pyridinemethanol; 5-Bromo-2-trifluoroacetylpyridine; 5-Bromo-2-pyridyl trifluoromethyl ketone
EINECS	Contact for details

Quality Control

Our 1-(5-Bromo-2-Pyridinyl)-2,2,2-Trifluoroethanone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from strong bases and reducing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.