Description

1-(2-Amino-1-m-Tolyl-Ethyl)-Pyrrolidine-3-Carboxylic Acid is a specialized chiral intermediate featuring a pyrrolidine carboxylic acid scaffold with an amino and a meta-tolyl substituent. This compound is of significant value in pharmaceutical research and development, serving as a key building block for the synthesis of complex bioactive molecules. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, particularly in areas requiring sophisticated chiral amine chemistry.

Application

• Pharmaceutical Intermediate: A critical chiral building block for the synthesis of novel active pharmaceutical ingredients (APIs), especially in central nervous system (CNS) and cardiovascular drug discovery.
• Organic Synthesis Reagent: Used in asymmetric synthesis and medicinal chemistry for constructing complex molecular architectures with high stereochemical purity.
• Ligand Precursor: Serves as a starting material for the development of chiral ligands and catalysts used in enantioselective transformations.
• Biochemical Research: Employed in the study of enzyme inhibitors and receptor modulators due to its structural similarity to natural amino acid derivatives.
• Custom Synthesis: A foundational component for contract research organizations (CROs) and CDMOs offering bespoke chemical synthesis services.

Basic Information

Product Name	1-(2-Amino-1-m-Tolyl-Ethyl)-Pyrrolidine-3-Carboxylic Acid
CAS No.	886363-94-6
Molecular Formula	C14H20N2O2
Molecular Weight	248.32 g/mol
Synonyms	3-Pyrrolidinecarboxylic acid, 1-[2-amino-1-(3-methylphenyl)ethyl]- (9CI); 1-[2-Amino-1-(3-methylphenyl)ethyl]pyrrolidine-3-carboxylic acid; (3R)-1-[(2S)-2-Amino-2-(3-methylphenyl)ethyl]pyrrolidine-3-carboxylic acid (for specific stereoisomers); m-Tolyl pyrrolidine carboxylic acid aminoethyl derivative; 886363-94-6; Pyrrolidine-3-carboxylic acid, 1-(2-amino-1-m-tolylethyl)-
EINECS	Contact for details

Quality Control

Our production of 1-(2-Amino-1-m-Tolyl-Ethyl)-Pyrrolidine-3-Carboxylic Acid adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced techniques including HPLC, chiral analysis, and NMR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing identity, purity, chiral purity, and impurity profiles is provided with every shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (for specific isomer)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.